There is a visual disorder called ‘stereo blindness’ and it is a reason for some people to be unable to watch movies in 3D or understand 3D as a whole. The main cause for this disability is that the eyes’ focus zone is not the same as with the others. In fact, it is a condition always present with patients with only one eye.
3D graphics’ depth of field is created by combining different images and using the eyes usual ability to focus in the middle of them. The whole process is impossible with stereo blind people. This means that Mr. Johny Depp cannot see either Alice in Wonderland, Pirates of the Caribbean or any other 3D movie since he would just see blue and red and green frames around the images.
According to some studies, this visual disorder is usually present in artists and even Rembrandt is believed to have had it.
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source:http://art2shere.blogspot.com/2012/11/135786640619773.html